Probiotic Bifidobacterium species: potential beneficial effects in diarrheal disorders. Focus on “Probiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells”
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منابع مشابه
Probiotic Bifidobacterium species: potential beneficial effects in diarrheal disorders. Focus on "Probiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells".
DIARRHEA CAUSED BY ENTERIC (bacterial/viral/parasitic) infections or diarrhea associated with inflammatory bowel disease represents a major health care burden worldwide (10). In addition, diarrhea associated with antibiotic administration in adults, as well as children, is a significant health care issue (1, 3). Diarrhea is also a common side effect of chemo/radiotherapy during cancer treatment...
متن کاملProbiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells.
SLC26A3, or downregulated in adenoma (DRA), plays a major role in mediating Cl(-) absorption in the mammalian intestine. Disturbances in DRA function and expression have been implicated in intestinal disorders such as congenital Cl(-) diarrhea and gut inflammation. We previously showed that an increase in DRA function and expression by Lactobacillus acidophilus and its culture supernatant (CS) ...
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Evidence has grown to support the efficacy of probiotics in the management of gastrointestinal disorders, many of which are associated with dysregulated fluid and electrolyte transport. A growing body of evidence now suggests that the host microbiota and probiotics can influence intestinal ion transport and that these effects often occur in a strain-dependent manner. In this study, we sought to...
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The intestinal tract is a diverse microenvironment where more than 500 species of bacteria thrive. A single layer of epithelium is all that separates these commensal microorganisms and pathogens from the underlying immune cells, and thus epithelial barrier function is a key component in the arsenal of defense mechanisms required to prevent infection and inflammation. The epithelial barrier cons...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Cell Physiology
سال: 2014
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00300.2014